Immunosuppressant therapeutic drug monitoring and trough level stabilisation after paediatric liver or kidney transplantation
نویسندگان
چکیده
منابع مشابه
A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...
متن کاملa review on therapeutic drug monitoring of immunosuppressant drugs
immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. this variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. drug monitoring is widely practiced ...
متن کاملA Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
: Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practice...
متن کاملPatient-reported non-adherence and immunosuppressant trough levels are associated with rejection after renal transplantation
BACKGROUND Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investigate whether graft rejection after renal transplantation is associated with patient-reported IS medication non-adherence and IS trough level variables (IS trough level variability...
متن کاملDrug level monitoring in paediatric practice.
A knowledge of the concentration of a drug in blood or other tissue fluid is now considered an important and sometimes essential part of the therapeutic management of various conditions. Its importance has increased as information showing wide interindividual variation in drug response has become recognised. Such variation arising from differences in absorption, distribution, and elimination ap...
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ژورنال
عنوان ژورنال: Swiss Medical Weekly
سال: 2019
ISSN: 1424-3997
DOI: 10.4414/smw.2019.20156